… of epigenetics, a term coined by Conrad Waddington in the 1940s, and how the epigenetic
approach to development differs from the genetic approach. Originally, epigenetics referred to …

… of epigenetic therapy, which is already making progress with the recent FDA approval of
three epigenetic … understanding of alterations in the epigenetic landscape that occur in cancer …

… The search for human equivalents of the epigenetic mechanisms … alter epigenetic states and
the same and/or similar epigenetic … in contrasting genetic vs epigenetic mechanisms in their …

… years that development is under epigenetic control. Epigenetics is the study of heritable …
The best‐studied epigenetic modifications are DNA methylation, and changes in chromatin …

… and epigenetic (CDGE) model provides an epidemiologic framework that can incorporate
epigenetic … Under CDGE, the epigenetic program can modify the effects of deleterious genes or …

… Although the definition that we choose for epigenetics has … Ultimately, it became useful to
redefine epigenetics so as to … “epigenetic” and “nonepigenetic” components are entwined. …

… Many types of epigenetic processes have been identified—they include methylation, …
epigenetic mechanisms and considerations are likely to surface as work proceeds. Epigenetic …

… Regardless of the exact definition, the epigenetic processes that … of the review, how epigenetics
interacts with gene expression, in … Epigenetic processes, including DNA methylation and …

… -wide epigenetic reprogramming drives the erasure and reestablishment of correct epigenetic
… Two specific types of epigenetic regulation established in early development include X-…

… to be epigenetic in nature and are believed to contribute to the normal processes of human
development but also to aberrant disease states such as cancer. Epigenetic … of epigenetics in …